RARB

Across TCGA cell cohorts, RARB mutation is significantly associated with the RNA expression of many other genes, with 545 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RARB-associated genes across cancer lineages are SYT10, MYF6, and GNGT1. Each is linked with RARB in more than 1 cancer types. Because this analysis shows association rather than direction, both RARB-to-partner and partner-to-RARB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SYT10 grouped by RARB-low versus RARB-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RARB→partner) and Y-score (partner→RARB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SYT10 →	+0.333	+4.339	.003	.002	3	1
BLOOD_Leukemia	MYF6 →	+0.128	+3.705	<.001	.007	3	1
BLOOD_Leukemia	GNGT1 →	+0.061	+3.551	<.001	.009	3	1
BLOOD_Leukemia	MYH8 →	+0.026	+4.984	<.001	.002	3	1
BLOOD_Leukemia	RGR →	+0.038	+4.269	<.001	.002	3	1
BLOOD_Leukemia	ANKRD33 →	+0.242	+4.269	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 545 associations by consensus.

SYT10 by RARB expression — BLOOD_Leukemia

Explore this box plot interactively →