RAP1B

Across TCGA cell cohorts, RAP1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,226 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RAP1B-associated GO terms across cancer lineages are Positive regulation of t-circle formation, Regulation of angiotensin-activated signaling pathway, and Regulation of microtubule depolymerization. Each is linked with RAP1B in more than 10 cancer types. Because this analysis shows association rather than direction, both RAP1B-to-partner and partner-to-RAP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of t-circle formation grouped by RAP1B-low versus RAP1B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP1B→partner) and Y-score (partner→RAP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of t-circle formation →	-0.168	-0.977	.001	.005	3	11
LUNG_NSCLC_LUSC	Regulation of angiotensin-activated signaling pathway →	+0.184	+0.824	<.001	<.001	3	10
BLOOD_Lymphoma	Regulation of microtubule depolymerization →	+0.068	+0.842	<.001	.002	3	10
OVARY	Interkinetic nuclear migration →	+0.075	+0.772	<.001	.001	3	10
BONE	Actin filament fragmentation →	+0.115	+0.971	<.001	.001	2	11
BLOOD_Leukemia	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.049	+0.675	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,226 associations by consensus.

Positive regulation of t-circle formation by RAP1B expression — URINARY_TRACT

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