RAMP1

Across TCGA patient cohorts, RAMP1 protein abundance is significantly associated with the RNA expression of many other genes, with 540 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RAMP1-associated genes across cancer lineages are ISX, MTCYBP9, and SEC14L2. Each is linked with RAMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAMP1-to-partner and partner-to-RAMP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAMP1 versus ISX in UCEC, with a Pearson correlation of 0.96.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAMP1→partner) and Y-score (partner→RAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ISX →	+0.190	+0.762	.002	.003	3	1
UCEC	MTCYBP9 →	+1.070	+0.762	<.001	.003	3	1
GBM	SEC14L2 →	+0.565	+0.902	<.001	<.001	3	1
GBM	GRK3 →	+0.404	+0.676	.006	.002	3	1
GBM	CHADL →	+0.679	+0.508	.005	.005	3	1
GBM	SALL4 →	-0.578	-0.502	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 540 associations by consensus.

RAMP1 vs ISX — UCEC

Explore this scatter interactively →