RAMP1

Across TCGA pan-cancer cohorts, RAMP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RAMP1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RAMP1 RNA is repressed in tumor relative to normal tissue. In most cancer types RAMP1 is over-expressed in tumor, although a few such as BLCA and KICH show the opposite, repressed pattern.

BLCA, KICH, and THCA are the cancer types where RAMP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAMP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−4.528	<.001	11	view →
KICH	Female	All	−3.820	<.001	11	view →
THCA	Male	All	+2.038	<.001	10	view →
KIRC	Male	II,III,IV	−1.762	<.001	10	view →
KIRP	Female	All	−1.982	<.001	9	view →
LUAD	Male	II,III,IV	+1.823	<.001	9	view →
BRCA	All	All	+1.895	<.001	8	view →
UCEC	All	All	−3.805	<.001	6	view →
LIHC	Male	All	+1.855	<.001	4	view →
READ	Female	All	−2.968	.020	3	view →
PRAD	All	All	+0.682	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RAMP1–BLCA

Open the BLCA breakdown →