RAMP1

Across TCGA cell cohorts, RAMP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,219 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RAMP1-associated GO terms across cancer lineages are Amylin receptor signaling pathway, Amylin receptor 1 signaling pathway, and Calcitonin gene-related peptide receptor signaling pathway. Each is linked with RAMP1 in more than 18 cancer types. Because this analysis shows association rather than direction, both RAMP1-to-partner and partner-to-RAMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Amylin receptor signaling pathway grouped by RAMP1-low versus RAMP1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAMP1→partner) and Y-score (partner→RAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Amylin receptor signaling pathway →	+2.152	+4.432	<.001	<.001	3	19
LIVER	Amylin receptor 1 signaling pathway →	+2.299	+3.800	<.001	<.001	3	19
LARGE_INTESTINE	Calcitonin gene-related peptide receptor signaling pathway →	+1.961	+3.618	<.001	<.001	3	17
OESOPHAGUS	Negative regulation of peptidase activity →	+0.322	+2.324	<.001	.004	3	8
SOFT_TISSUE	Mitochondrial respirasome assembly →	+0.065	+0.854	.005	.002	3	7
LUNG_NSCLC_LUSC	Blood vessel endothelial cell fate commitment →	+0.300	+3.768	.003	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,219 associations by consensus.

Amylin receptor signaling pathway by RAMP1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →