RAI14

Across TCGA cell cohorts, RAI14 mutation is significantly associated with the RNA expression of many other genes, with 571 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAI14-associated genes across cancer lineages are H2BW2, ASCL4, and GRM4. Each is linked with RAI14 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAI14-to-partner and partner-to-RAI14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H2BW2 grouped by RAI14-low versus RAI14-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAI14→partner) and Y-score (partner→RAI14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	H2BW2 →	+0.063	+3.556	.001	.001	3	2
BLOOD_Leukemia	ASCL4 →	+0.584	+3.772	<.001	<.001	3	2
LARGE_INTESTINE	GRM4 →	+0.764	+2.714	<.001	.004	3	2
LARGE_INTESTINE	LYSMD1 →	+0.505	+3.131	.004	.008	3	2
OESOPHAGUS	CD1C →	+0.013	+4.017	.002	.007	3	1
OESOPHAGUS	ANHX →	+0.038	+4.392	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 571 associations by consensus.

H2BW2 by RAI14 expression — BLOOD_Leukemia

Explore this box plot interactively →