RAI14

Across TCGA pan-cancer cohorts, RAI14 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RAI14 data layer compared with 12 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher RAI14 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAI14 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

MESO, STAD, and KIRC are the cancer types where RAI14 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	II,III,IV	0.243	0.493	.001	109	view →
STAD	DFS	Median	All	0.303	0.501	.001	107	view →
KIRC	DFS	Tertile	All	0.746	0.449	<.001	70	view →
KIRP	DFS	Tertile	All	0.753	0.926	<.001	68	view →
UVM	DFS	Median	II,III,IV	0.327	0.755	<.001	61	view →
LGG	OS	Median	All	0.725	0.890	<.001	52	view →
COAD	DFS	Tertile	All	0.706	0.870	.003	35	view →
UCS	DFS	Tertile	IV	0.832	0.239	.024	24	view →
KICH	OS	Quartile	II,III,IV	0.651	1.000	.019	14	view →
CESC	DFS	Median	All	0.778	0.863	.007	14	view →
THCA	OS	Median	II,III,IV	0.956	0.998	.012	13	view →
LIHC	DFS	Quartile	All	0.359	0.515	.007	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

RAI14–MESO (DFS)

Open the MESO breakdown →