RAD54L2

Across TCGA cell cohorts, RAD54L2 mutation is significantly associated with the mutation status of many other genes, with 4,974 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAD54L2-associated genes across cancer lineages are CAPN15, REV1, and BCL11B. Each is linked with RAD54L2 in more than 5 cancer types. Because this analysis shows association rather than direction, both RAD54L2-to-partner and partner-to-RAD54L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAPN15 grouped by RAD54L2-low versus RAD54L2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD54L2→partner) and Y-score (partner→RAD54L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CAPN15 →	+4.942	+4.942	.001	.001	1	6
CNS	REV1 →	+5.277	+4.459	.005	.005	1	5
LUNG_NSCLC_LUAD	BCL11B →	+3.303	+3.478	.006	.006	1	5
CNS	KCNQ5 →	+5.277	+4.459	.005	.005	1	4
CNS	WWP2 →	+5.277	+4.459	.005	.005	1	4
LARGE_INTESTINE	BMPER →	+2.925	+2.514	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,974 associations by consensus.

CAPN15 by RAD54L2 expression — STOMACH

Explore this box plot interactively →