RAD51AP1

Across TCGA patient cohorts, RAD51AP1 mutation is significantly associated with the RNA expression of many other genes, with 789 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAD51AP1-associated genes across cancer lineages are RNA5SP86, MTL3P, and MIR4524B. Each is linked with RAD51AP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAD51AP1-to-partner and partner-to-RAD51AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP86 grouped by RAD51AP1-low versus RAD51AP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD51AP1→partner) and Y-score (partner→RAD51AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP86 →	+0.537	+2.621	<.001	.002	3	3
CESC	MTL3P →	+0.458	+6.144	<.001	.001	3	2
CESC	MIR4524B →	+0.295	+5.201	<.001	.007	3	2
UCEC	RNA5SP502 →	+0.727	+2.293	<.001	<.001	3	2
UCEC	SNORA35 →	+0.070	+3.812	<.001	.008	3	2
UCEC	TRAJ27 →	+0.716	+2.060	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 789 associations by consensus.

RNA5SP86 by RAD51AP1 expression — UCEC

Explore this box plot interactively →