Q-omics provides the consensus-scored MTL3P profile across patient tissues and cancer cell-line models. MTL3P expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in MESO. Additionally, MTL3P RNA expression shows 5,884 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight MESO, and STAD as cancer lineages where MTL3P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MTL3P survival associations across molecular data types. MTL3P RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MTL3P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	MESO (63)	view →

This table ranks reproducible MTL3P RNA expression–survival associations across cancer types. High MTL3P expression shows unfavorable associations in MESO, HNSC, LUAD, SARC and LIHC, but favorable associations in ESCA. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .004). Together, the overview and detailed table identify MESO as the clearest survival context for MTL3P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	III,IV	0.137	0.389	.004	63	view →
HNSC	OS	Tertile	III,IV	0.305	0.693	.001	36	view →
LUAD	OS	Tertile	All	0.455	0.837	.001	33	view →
ESCA	OS	Tertile	III,IV	1.000	0.381	.033	18	view →
SARC	OS	Tertile	All	0.592	0.842	.016	18	view →
LIHC	OS	Tertile	All	0.284	0.711	.036	9	view →

Pink = unfavorable, green = favorable. all 7 lineages →

MTL3P-MESO (DFS)

Kaplan–Meier survival curve for MTL3P RNA expression in MESO: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MTL3P in patient tissues and cancer cell lines. In patient samples, MTL3P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,884	STAD (5502)	view →
RNA	2,848	ESCA (635)	view →