MTL3P

Across TCGA pan-cancer cohorts, MTL3P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated MTL3P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MTL3P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTL3P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

MESO, HNSC, and LUAD are the cancer types where MTL3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	III,IV	0.137	0.389	.004	63	view →
HNSC	OS	Tertile	III,IV	0.305	0.693	.001	36	view →
LUAD	OS	Tertile	All	0.455	0.837	.001	33	view →
ESCA	OS	Tertile	III,IV	1.000	0.381	.033	18	view →
SARC	OS	Tertile	All	0.592	0.842	.016	18	view →
LIHC	OS	Tertile	All	0.284	0.711	.036	9	view →
UCEC	DFS	Tertile	All	0.654	0.842	.042	6	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MTL3P–MESO (DFS)

Open the MESO breakdown →