RABL2B

Across TCGA cell cohorts, RABL2B mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RABL2B-associated genes across cancer lineages are LYPD4, OR2F1, and IQCF6. Each is linked with RABL2B in more than 1 cancer types. Because this analysis shows association rather than direction, both RABL2B-to-partner and partner-to-RABL2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LYPD4 grouped by RABL2B-low versus RABL2B-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABL2B→partner) and Y-score (partner→RABL2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	LYPD4 →	+0.025	+3.392	<.001	.007	3	1
BLOOD_Leukemia	OR2F1 →	+0.006	+3.269	.003	.007	3	1
BLOOD_Leukemia	IQCF6 →	+0.261	+3.091	.004	.006	3	1
BLOOD_Leukemia	KIR2DS4 →	+0.414	+3.556	<.001	.001	3	1
CNS	HAO1 →	+0.660	+2.984	<.001	.007	3	1
CNS	CST4 →	+0.727	+3.096	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

LYPD4 by RABL2B expression — OESOPHAGUS

Explore this box plot interactively →