RABL2B

Across TCGA pan-cancer cohorts, RABL2B RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RABL2B data layer compared with 1 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher RABL2B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RABL2B expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCEC show a favorable association.

MESO, LIHC, and BLCA are the cancer types where RABL2B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	II,III,IV	0.302	0.580	.001	79	view →
LIHC	DFS	Median	All	0.470	0.611	<.001	73	view →
BLCA	DFS	Quartile	IV	0.638	0.396	.008	68	view →
ACC	DFS	Tertile	All	0.214	0.699	<.001	52	view →
UCEC	DFS	Quartile	All	0.962	0.862	.001	48	view →
READ	OS	Tertile	II,III,IV	0.793	0.262	<.001	39	view →
LGG	DFS	Tertile	All	0.653	0.821	<.001	36	view →
HNSC	OS	Median	All	0.621	0.799	.002	32	view →
KIRC	DFS	Quartile	All	0.537	0.694	.007	31	view →
LUSC	DFS	Median	III,IV	0.540	0.761	.002	27	view →
THCA	DFS	Tertile	IV	0.498	0.865	.013	24	view →
KICH	OS	Tertile	All	0.679	1.000	.020	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RABL2B–MESO (OS)

Open the MESO breakdown →