RABGGTB

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RABGGTB mutation is significantly associated with the RNA expression of many other genes, with 1,789 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABGGTB-associated genes across cancer lineages are RNA5SP411, RNU6-1042P, and RPL23AP4. Each is linked with RABGGTB in more than 1 cancer types. Because this analysis shows association rather than direction, both RABGGTB-to-partner and partner-to-RABGGTB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by RABGGTB-low versus RABGGTB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGGTB→partner) and Y-score (partner→RABGGTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP411 →+0.817+1.863.002.00332
READRNU6-1042P →+0.598+5.039<.001.00832
READRPL23AP4 →+0.171+5.039<.001.00832
UCECRNA5SP405 →+0.197+2.919<.001.00732
COADMIR147A →+0.486+4.308<.001.00932
HNSCRNY4P14 →+0.187+4.468<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,789 associations by consensus.

RNA5SP411 by RABGGTB expression — UCEC

Box plot of RNA5SP411 in RABGGTB-low vs RABGGTB-high samples in UCEC.

Explore this box plot interactively →

Exploration