RABGGTB

Across TCGA pan-cancer cohorts, RABGGTB RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RABGGTB’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RABGGTB RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RABGGTB is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, THCA, and LIHC are the cancer types where RABGGTB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RABGGTB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	+0.850	<.001	12	view →
THCA	Male	III,IV	+0.669	<.001	11	view →
LIHC	All	II,III,IV	+1.140	<.001	9	view →
COAD	Male	All	+0.680	<.001	8	view →
BLCA	All	III,IV	+0.577	.001	8	view →
READ	All	All	+0.877	<.001	7	view →
STAD	All	II,III,IV	+0.831	<.001	7	view →
HNSC	Female	III,IV	+0.382	.007	7	view →
BRCA	All	II,III,IV	+0.349	<.001	6	view →
CHOL	Female	All	+2.656	<.001	5	view →
ESCA	All	II,III,IV	+0.820	.007	4	view →
KICH	Female	All	−0.712	.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RABGGTB–KIRC

Open the KIRC breakdown →