RABGAP1

Across TCGA patient cohorts, RABGAP1 mutation is significantly associated with the RNA expression of many other genes, with 6,163 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABGAP1-associated genes across cancer lineages are HAUS8, CCNB2, and CCL18. Each is linked with RABGAP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RABGAP1-to-partner and partner-to-RABGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HAUS8 grouped by RABGAP1-low versus RABGAP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGAP1→partner) and Y-score (partner→RABGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HAUS8 →	+0.385	+1.966	<.001	<.001	3	4
UCEC	CCNB2 →	+0.705	+2.137	<.001	<.001	3	4
UCEC	CCL18 →	+1.429	+1.807	<.001	<.001	3	3
COAD	RNU6-709P →	+0.367	+4.557	<.001	.004	3	3
CESC	RNU6-838P →	+0.178	+3.729	<.001	.002	3	3
LUAD	LMNB1 →	+0.917	+3.345	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,163 associations by consensus.

HAUS8 by RABGAP1 expression — UCEC

Explore this box plot interactively →