RABEP1

Across TCGA patient cohorts, RABEP1 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABEP1-associated genes across cancer lineages are Caspase-7-cleavedD198, p27_pT198, and beta-Catenin. Each is linked with RABEP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RABEP1-to-partner and partner-to-RABEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by RABEP1-low versus RABEP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABEP1→partner) and Y-score (partner→RABEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.677	+1.785	<.001	.007	3	3
UCEC	p27_pT198 →	+0.087	+2.584	.018	.010	3	2
UCEC	beta-Catenin →	+0.428	+1.736	.014	.007	3	2
UCEC	EGFR_pY1068 →	-0.223	-1.736	.010	.007	3	1
UCEC	ERK2 →	+0.205	+2.906	.002	.001	3	1
UCEC	FoxM1 →	+0.235	+2.070	.008	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Caspase-7-cleavedD198 by RABEP1 expression — UCEC

Explore this box plot interactively →