RABEP1

Across TCGA pan-cancer cohorts, RABEP1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated RABEP1 data layer compared with 7 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher RABEP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RABEP1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

MESO, KICH, and KIRC are the cancer types where RABEP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Quartile	III,IV	0.197	0.540	.003	58	view →
KICH	OS	Quartile	All	0.580	1.000	.001	54	view →
KIRC	DFS	Median	All	0.744	0.503	.001	50	view →
UVM	DFS	Tertile	III,IV	0.229	0.860	.001	47	view →
BRCA	OS	Median	III,IV	0.958	0.846	<.001	43	view →
SCLC	DFS	Quartile	All	0.425	0.129	.016	31	view →
THYM	DFS	Tertile	II,III,IV	0.925	0.448	.011	22	view →
DLBC	DFS	Quartile	All	0.619	1.000	.015	22	view →
PAAD	DFS	Tertile	All	0.350	0.193	.013	18	view →
GBM	DFS	Tertile	All	0.397	0.138	.002	18	view →
ESCA	OS	Tertile	IV	0.143	0.738	.024	18	view →
LUSC	DFS	Quartile	III,IV	0.227	0.903	.001	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

RABEP1–MESO (DFS)

Open the MESO breakdown →