RABAC1

Across TCGA patient cohorts, RABAC1 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABAC1-associated genes across cancer lineages are RPL23AP84, CHEK2P5, and SNORD114-5. Each is linked with RABAC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RABAC1-to-partner and partner-to-RABAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP84 grouped by RABAC1-low versus RABAC1-high in KIRP.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABAC1→partner) and Y-score (partner→RABAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	RPL23AP84 →	+0.102	+5.264	<.001	.006	3	2
KIRP	CHEK2P5 →	+0.179	+4.967	.003	.009	3	2
BLCA	SNORD114-5 →	+0.336	+7.640	<.001	.009	3	1
BLCA	RNU6-984P →	+0.193	+7.640	<.001	.009	3	1
BLCA	RNU6-211P →	+0.238	+7.640	<.001	.009	3	1
UCEC	MIR6129 →	+0.628	+3.496	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

RPL23AP84 by RABAC1 expression — KIRP

Explore this box plot interactively →