RAB5C

Across TCGA patient cohorts, RAB5C RNA expression is significantly associated with the mutation status of many other genes, with 9,326 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB5C-associated genes across cancer lineages are TP53, TTN, and PIK3CA. Each is linked with RAB5C in more than 3 cancer types. Because this analysis shows association rather than direction, both RAB5C-to-partner and partner-to-RAB5C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by RAB5C-low versus RAB5C-high in LIHC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB5C→partner) and Y-score (partner→RAB5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TP53 →	+0.981	+0.229	<.001	.004	3	4
UCEC	TTN →	+0.769	+0.308	<.001	<.001	3	4
BRCA	PIK3CA →	+0.649	+0.184	<.001	<.001	3	3
UCEC	PCDH11X →	+2.257	+0.416	<.001	<.001	3	3
LUSC	UNC13C →	+2.140	+0.207	<.001	<.001	3	3
LUAD	LRRIQ1 →	+1.672	+0.248	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,326 associations by consensus.

TP53 by RAB5C expression — LIHC

Explore this box plot interactively →