RAB5C

Across TCGA patient cohorts, RAB5C mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB5C-associated genes across cancer lineages are Epithelial cells and pDC. Each is linked with RAB5C in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB5C-to-partner and partner-to-RAB5C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cells grouped by RAB5C-low versus RAB5C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB5C→partner) and Y-score (partner→RAB5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.129	-3.000	.001	.037	3	1
UCEC	pDC →	+0.098	+3.010	<.001	.020	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Epithelial cells by RAB5C expression — UCEC

Explore this box plot interactively →