RAB5C

Across TCGA cell cohorts, RAB5C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,439 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RAB5C-associated GO terms across cancer lineages are Endosomal vesicle fusion, Retrograde transport, endosome to Golgi, and Protein depolymerization. Each is linked with RAB5C in more than 12 cancer types. Because this analysis shows association rather than direction, both RAB5C-to-partner and partner-to-RAB5C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal vesicle fusion grouped by RAB5C-low versus RAB5C-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB5C→partner) and Y-score (partner→RAB5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Endosomal vesicle fusion →	+0.107	+1.004	<.001	<.001	3	13
SKIN	Retrograde transport, endosome to Golgi →	+0.077	+0.994	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Protein depolymerization →	+0.100	+0.896	<.001	<.001	3	13
SKIN	Endosomal transport →	+0.071	+1.076	<.001	<.001	3	12
OESOPHAGUS	Regulation of Golgi inheritance →	+0.157	+0.599	<.001	.004	3	12
LARGE_INTESTINE	Negative regulation of intracellular estrogen receptor signaling pathway →	+0.143	+0.931	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,439 associations by consensus.

Endosomal vesicle fusion by RAB5C expression — SKIN

Explore this box plot interactively →