RAB44

Across TCGA patient cohorts, RAB44 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB44-associated genes across cancer lineages are RN7SL248P, HMGB4, and OR7E18P. Each is linked with RAB44 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB44-to-partner and partner-to-RAB44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by RAB44-low versus RAB44-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB44→partner) and Y-score (partner→RAB44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.124	+4.400	<.001	.006	3	2
CESC	HMGB4 →	+0.015	+5.306	<.001	.006	3	1
CESC	OR7E18P →	+0.068	+6.342	<.001	.001	3	1
CESC	RNU1-62P →	+0.339	+5.539	<.001	.004	3	1
CESC	LINC01870 →	+0.125	+7.164	<.001	<.001	3	1
CESC	CDK2AP2P3 →	+0.121	+5.201	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

RN7SL248P by RAB44 expression — UCEC

Explore this box plot interactively →