RAB44

Across TCGA pan-cancer cohorts, RAB44 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of RAB44’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RAB44 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAB44 is over-expressed in tumor, although a few such as LUAD and COAD show the opposite, repressed pattern.

THCA, LUAD, and COAD are the cancer types where RAB44 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB44 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	III,IV	+0.101	<.001	10	view →
LUAD	Male	II,III,IV	−0.713	<.001	9	view →
COAD	Female	II,III,IV	−0.250	<.001	9	view →
KIRC	All	All	+0.129	<.001	9	view →
LUSC	Male	II,III,IV	−0.825	<.001	8	view →
UCEC	All	All	−0.475	<.001	4	view →
BLCA	Female	All	−0.361	.012	3	view →
KIRP	All	All	+0.189	.036	1	view →
CHOL	All	All	+0.064	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

RAB44–THCA

Open the THCA breakdown →