RAB44

Across TCGA cell cohorts, RAB44 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB44-associated genes across cancer lineages are MOGAT1, ABCA9, and CCDC42. Each is linked with RAB44 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB44-to-partner and partner-to-RAB44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MOGAT1 grouped by RAB44-low versus RAB44-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB44→partner) and Y-score (partner→RAB44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MOGAT1 →	+0.107	+2.878	<.001	.009	3	1
LARGE_INTESTINE	ABCA9 →	+0.110	+3.520	<.001	.005	3	1
LARGE_INTESTINE	CCDC42 →	+0.040	+2.925	<.001	.007	3	1
LARGE_INTESTINE	FAM47C →	+0.008	+3.217	<.001	.006	3	1
LARGE_INTESTINE	FAM24A →	+0.035	+3.700	<.001	.009	3	1
LARGE_INTESTINE	FAM153CP →	+0.284	+3.539	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

MOGAT1 by RAB44 expression — LARGE_INTESTINE

Explore this box plot interactively →