RAB40A

Across TCGA patient cohorts, RAB40A mutation is significantly associated with the RNA expression of many other genes, with 1,780 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB40A-associated genes across cancer lineages are RN7SKP226, MIR4663, and IGLVV-66. Each is linked with RAB40A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB40A-to-partner and partner-to-RAB40A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP226 grouped by RAB40A-low versus RAB40A-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB40A→partner) and Y-score (partner→RAB40A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SKP226 →	+0.488	+6.081	<.001	.002	3	2
LUSC	MIR4663 →	+0.572	+5.337	<.001	.006	3	2
COAD	IGLVV-66 →	+0.238	+6.547	.002	.001	3	2
UCEC	SNORD115-20 →	+0.113	+4.086	<.001	.005	3	2
BRCA	MIR6811 →	+0.434	+4.841	<.001	.006	3	1
UCEC	ESS2 →	+0.299	+2.747	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,780 associations by consensus.

RN7SKP226 by RAB40A expression — LUSC

Explore this box plot interactively →