RAB40A

Across TCGA pan-cancer cohorts, RAB40A RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RAB40A data layer compared with 3 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher RAB40A RNA is associated with better overall survival. In most high-consensus cancer types, elevated RAB40A expression acts as an unfavorable survival marker, although some lineages such as MESO and READ show a favorable association.

MESO, KIRC, and READ are the cancer types where RAB40A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.508	0.272	<.001	52	view →
KIRC	DFS	Median	All	0.509	0.692	.003	38	view →
READ	OS	Median	IV	0.913	0.473	<.001	31	view →
SKCM	DFS	Tertile	All	0.254	0.142	.002	26	view →
UCS	DFS	Tertile	IV	0.956	0.422	.024	24	view →
UVM	DFS	Quartile	III,IV	0.278	0.914	.005	23	view →
CESC	DFS	Quartile	All	0.431	0.711	.002	22	view →
STAD	DFS	Tertile	All	0.487	0.646	.007	22	view →
UCEC	DFS	Quartile	All	0.598	0.803	.004	18	view →
COAD	DFS	Quartile	IV	0.813	0.328	.024	15	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	13	view →
BLCA	OS	Median	II,III,IV	0.656	0.559	.036	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RAB40A–MESO (OS)

Open the MESO breakdown →