Q-omics provides the consensus-scored IGLVV-66 profile across patient tissues and cancer cell-line models. IGLVV-66 expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in LUSC. Additionally, IGLVV-66 RNA expression shows 5,881 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight LUSC, and STAD as cancer lineages where IGLVV-66 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes IGLVV-66 survival associations across molecular data types. IGLVV-66 RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

IGLVV-66 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	LUSC (63)	view →

This table ranks reproducible IGLVV-66 RNA expression–survival associations across cancer types. High IGLVV-66 expression shows unfavorable associations in LUSC, ESCA, OV and SKCM, but favorable associations in LGG and PAAD. The LUSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .014). Together, the overview and detailed table identify LUSC as the clearest survival context for IGLVV-66 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	III,IV	0.203	0.575	.014	63	view →
ESCA	DFS	Tertile	All	0.148	0.673	.040	18	view →
OV	OS	Tertile	II,III,IV	0.528	0.845	.017	18	view →
LGG	DFS	Tertile	All	0.973	0.823	.024	12	view →
PAAD	OS	Tertile	II,III,IV	0.779	0.348	.018	12	view →
SKCM	OS	Tertile	III,IV	0.219	0.702	.002	9	view →

Pink = unfavorable, green = favorable. all 7 lineages →

IGLVV-66-LUSC (OS)

Kaplan–Meier survival curve for IGLVV-66 RNA expression in LUSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with IGLVV-66 in patient tissues and cancer cell lines. In patient samples, IGLVV-66 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,881	STAD (5213)	view →
RNA	3,272	HNSC (1253)	view →