RAB3GAP1

Across TCGA cell cohorts, RAB3GAP1 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB3GAP1-associated genes across cancer lineages are EPPIN, OR3A1, and FIGLA. Each is linked with RAB3GAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB3GAP1-to-partner and partner-to-RAB3GAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPPIN grouped by RAB3GAP1-low versus RAB3GAP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3GAP1→partner) and Y-score (partner→RAB3GAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	OR3A1 →	+1.055	+4.922	<.001	.009	3	1
BLOOD_Leukemia	FIGLA →	+0.036	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	OR1D4 →	+0.052	+5.539	<.001	.003	3	1
BLOOD_Lymphoma	C16orf92 →	+0.095	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	OR56A4 →	+0.043	+4.927	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

EPPIN by RAB3GAP1 expression — BLOOD_Leukemia

Explore this box plot interactively →