RAB3C

Across TCGA patient cohorts, RAB3C mutation is significantly associated with the RNA expression of many other genes, with 623 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB3C-associated genes across cancer lineages are MIR4802, RNU6-997P, and RNU6-33P. Each is linked with RAB3C in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB3C-to-partner and partner-to-RAB3C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4802 grouped by RAB3C-low versus RAB3C-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3C→partner) and Y-score (partner→RAB3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4802 →	+0.417	+4.797	<.001	.003	3	2
ESCA	RNU6-997P →	+0.471	+5.450	<.001	.004	3	2
UCEC	RNU6-33P →	+0.519	+2.437	.001	<.001	3	2
UCEC	RPL34P3 →	+0.105	+2.511	.008	.003	3	2
UCEC	MTND3P2 →	+0.234	+3.045	<.001	.002	3	2
UCEC	TAF11L14 →	+0.302	+1.908	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 623 associations by consensus.

MIR4802 by RAB3C expression — SKCM

Explore this box plot interactively →