RNU6-997P

associated omics data
RNA, U6 small nuclear 997, pseudogeneGenealiases: []

Q-omics provides the consensus-scored RNU6-997P profile across patient tissues and cancer cell-line models. RNU6-997P expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, RNU6-997P is differentially expressed in 1, with the highest sampling consensus in BRCA. Additionally, RNU6-997P RNA expression shows 5,288 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KICH, BRCA, and STAD as cancer lineages where RNU6-997P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-997P survival associations across molecular data types. RNU6-997P RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
RNU6-997P data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier11MESO (90)view →
This table ranks reproducible RNU6-997P RNA expression–survival associations across cancer types. High RNU6-997P expression shows unfavorable associations in KICH, MESO, KIRP, TGCT, DLBC and HNSC. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for RNU6-997P RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KICHDFSTertileAll0.0810.904<.00190view →
MESOOSTertileIII,IV0.0770.580<.00190view →
KIRPOSTertileII,III,IV0.1610.771.00272view →
TGCTDFSTertileII,III,IV0.0150.919<.00136view →
DLBCDFSTertileII,III,IV0.0220.837<.00136view →
HNSCOSTertileIV0.1620.639.03036view →
Pink = unfavorable, green = favorable. all 11 lineages →

RNU6-997P-KICH (DFS)

Kaplan–Meier survival curve for RNU6-997P RNA expression in KICH: high vs low expression groups.

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Tumor vs Normal expression

This table summarizes RNU6-997P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in BRCA for RNA.
RNU6-997P data typeExpression analysisLineage consensusLineage of highest sampling consensus
RNABox plot1BRCA (4)view →
This table ranks reproducible tumor–normal expression differences for RNU6-997P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-997P shows higher tumor expression in BRCA. The BRCA box plot shows higher RNU6-997P RNA expression in tumor versus normal tissue (log2 FC = +0.120, t-test p = .006).
LineageGenderStageFold-changepSampling consensus
BRCAFemaleAll+0.120.0064view →
Green = repressed in tumor. all 1 lineages →

RNU6-997P-BRCA

Tumor-vs-normal expression box plot for RNU6-997P in BRCA.

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Cross-omics associations

This table shows molecular features associated with RNU6-997P in patient tissues and cancer cell lines. In patient samples, RNU6-997P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
Function (RNA)5,288STAD (4978)view →
Protein (mass-spec)3,000GBM (1408)view →