RAB3B

Across TCGA patient cohorts, RAB3B mutation is significantly associated with the RNA expression of many other genes, with 652 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB3B-associated genes across cancer lineages are SNRPCP20, RNU6-794P, and PYDC2. Each is linked with RAB3B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB3B-to-partner and partner-to-RAB3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPCP20 grouped by RAB3B-low versus RAB3B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3B→partner) and Y-score (partner→RAB3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SNRPCP20 →	+0.145	+4.588	<.001	<.001	3	2
BLCA	RNU6-794P →	+0.225	+4.814	<.001	.003	3	1
BLCA	PYDC2 →	+0.152	+4.095	.002	.001	3	1
BLCA	LINC01608 →	+1.176	+4.029	.009	.003	3	1
BLCA	OR8A2P →	+0.128	+3.396	.005	.006	3	1
BLCA	LINC02304 →	+0.059	+4.147	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 652 associations by consensus.

SNRPCP20 by RAB3B expression — BLCA

Explore this box plot interactively →