RAB39B

Across TCGA patient cohorts, RAB39B mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB39B-associated genes across cancer lineages are JNK2, S6_pS240_S244, and ATM. Each is linked with RAB39B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB39B-to-partner and partner-to-RAB39B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by RAB39B-low versus RAB39B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB39B→partner) and Y-score (partner→RAB39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.213	+2.469	.007	.010	3	2
UCEC	S6_pS240_S244 →	+0.386	+3.013	.018	.018	3	2
UCEC	ATM →	-0.533	-2.415	.003	.003	3	2
UCEC	Caspase-7-cleavedD198 →	+0.636	+2.479	.007	.010	3	2
UCEC	4E-BP1 →	+0.249	+2.321	.022	.033	3	2
UCEC	EGFR_pY1068 →	-0.226	-2.415	.025	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

JNK2 by RAB39B expression — UCEC

Explore this box plot interactively →