RAB39B

Across TCGA cell cohorts, RAB39B mutation is significantly associated with the mutation status of many other genes, with 908 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB39B-associated genes across cancer lineages are RTN4, ZNF597, and ZNF608. Each is linked with RAB39B in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB39B-to-partner and partner-to-RAB39B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RTN4 grouped by RAB39B-low versus RAB39B-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB39B→partner) and Y-score (partner→RAB39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	RTN4 →	+4.459	+5.277	.005	.005	1	3
LARGE_INTESTINE	ZNF597 →	+4.523	+5.087	.006	.006	1	2
CNS	ZNF608 →	+4.459	+5.277	.005	.005	1	2
CNS	KAT5 →	+4.459	+5.277	.005	.005	1	2
CNS	FZD4 →	+6.044	+6.044	.001	.001	1	2
CNS	DENND5A →	+4.459	+5.277	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 908 associations by consensus.

RTN4 by RAB39B expression — CNS

Explore this box plot interactively →