RAB38

Across TCGA pan-cancer cohorts, RAB38 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RAB38 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RAB38 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB38 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

CCRCC, HNSC, and LSCC are the cancer types where RAB38 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.212	0.870	<.001	72	view →
HNSC	OS	Median	All	0.800	0.618	.015	13	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.814	.011	8	view →
PDAC	DFS	Tertile	II,III,IV	0.857	0.313	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RAB38–CCRCC (DFS)

Open the CCRCC breakdown →