RAB36

Across TCGA patient cohorts, RAB36 mutation is significantly associated with the RNA expression of many other genes, with 550 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB36-associated genes across cancer lineages are MIR16-2, MIR615, and EEF1E1-BLOC1S5. Each is linked with RAB36 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB36-to-partner and partner-to-RAB36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR16-2 grouped by RAB36-low versus RAB36-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB36→partner) and Y-score (partner→RAB36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	MIR16-2 →	+0.398	+7.977	<.001	.007	3	3
COAD	MIR615 →	+0.757	+4.693	<.001	.007	3	2
COAD	EEF1E1-BLOC1S5 →	+0.059	+4.516	<.001	.009	3	2
SKCM	LINC02143 →	+0.091	+5.867	<.001	.003	3	2
UCEC	M6PRP1 →	+0.043	+2.773	.003	.004	3	2
LUSC	RNA5SP235 →	+0.261	+3.739	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 550 associations by consensus.

MIR16-2 by RAB36 expression — LGG

Explore this box plot interactively →