RAB36

Across TCGA pan-cancer cohorts, RAB36 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RAB36 data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RAB36 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RAB36 expression acts as an unfavorable survival marker, although some lineages such as KIRP and HNSC show a favorable association.

KIRP, LGG, and HNSC are the cancer types where RAB36 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	1.000	0.714	.001	65	view →
LGG	OS	Median	All	0.724	0.892	<.001	51	view →
HNSC	OS	Median	All	0.811	0.722	.012	33	view →
READ	DFS	Quartile	III,IV	0.933	0.588	.008	26	view →
LAML	DFS	Tertile	All	0.445	0.632	.014	26	view →
CESC	OS	Quartile	All	0.777	0.469	.002	22	view →
CHOL	OS	Quartile	All	0.892	0.184	.006	18	view →
PCPG	DFS	Quartile	All	0.939	0.637	.001	17	view →
KIRC	DFS	Quartile	All	0.734	0.494	.001	16	view →
SARC	DFS	Tertile	All	0.697	0.546	.005	16	view →
THYM	OS	Median	All	0.694	0.973	<.001	13	view →
ESCA	OS	Median	IV	0.698	0.222	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RAB36–KIRP (OS)

Open the KIRP breakdown →