RAB36

Across TCGA pan-cancer cohorts, RAB36 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RAB36’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RAB36 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAB36 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

COAD, KICH, and THCA are the cancer types where RAB36 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB36 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.925	<.001	11	view →
KICH	Female	III,IV	−1.679	<.001	11	view →
THCA	Male	All	−0.870	<.001	8	view →
KIRP	All	All	+0.490	.006	7	view →
HNSC	Male	II,III,IV	+0.687	.001	6	view →
LUAD	All	II,III,IV	−0.671	.003	6	view →
KIRC	Female	All	+0.493	<.001	5	view →
CHOL	Male	All	+3.661	<.001	3	view →
READ	All	All	+1.178	.016	3	view →
BLCA	Female	III,IV	+0.738	.026	1	view →
LIHC	Male	All	−0.214	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RAB36–COAD

Open the COAD breakdown →