RAB2A

Across TCGA cell cohorts, RAB2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,993 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RAB2A-associated GO terms across cancer lineages are Synaptic vesicle lumen acidification, Synaptic vesicle maturation, and Endosomal lumen acidification. Each is linked with RAB2A in more than 10 cancer types. Because this analysis shows association rather than direction, both RAB2A-to-partner and partner-to-RAB2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Synaptic vesicle lumen acidification grouped by RAB2A-low versus RAB2A-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB2A→partner) and Y-score (partner→RAB2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Synaptic vesicle lumen acidification →	+0.178	+1.018	<.001	<.001	3	11
BONE	Synaptic vesicle maturation →	+0.122	+0.756	.004	.003	3	10
LIVER	Endosomal lumen acidification →	+0.180	+1.236	<.001	<.001	3	10
LUNG_SCLC	Golgi organization →	+0.061	+0.788	.005	<.001	3	10
LUNG_SCLC	Endosome organization →	+0.061	+0.965	<.001	<.001	3	10
SKIN	Macroautophagy →	+0.032	+0.544	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,993 associations by consensus.

Synaptic vesicle lumen acidification by RAB2A expression — SOFT_TISSUE

Explore this box plot interactively →