RAB2A

Across TCGA pan-cancer cohorts, RAB2A RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of RAB2A’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RAB2A RNA is repressed in tumor relative to normal tissue. In most cancer types RAB2A is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, LIHC, and HNSC are the cancer types where RAB2A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB2A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−0.659	<.001	9	view →
LIHC	Male	II,III,IV	+1.045	<.001	8	view →
HNSC	Female	IV	+0.938	<.001	8	view →
STAD	All	All	+0.390	.003	8	view →
LUAD	Male	II,III,IV	+0.579	<.001	6	view →
BRCA	All	III,IV	+0.535	<.001	6	view →
CHOL	All	All	+0.985	<.001	4	view →
KICH	All	All	−0.488	.002	4	view →
BLCA	Male	All	+0.256	.022	2	view →
ESCA	All	All	+0.451	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

RAB2A–THCA

Open the THCA breakdown →