RAB27B

Across TCGA patient cohorts, RAB27B protein abundance is significantly associated with the RNA expression of many other genes, with 17,453 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RAB27B-associated genes across cancer lineages are TCN1, CCDC68, and GTF2IP7. Each is linked with RAB27B in more than 6 cancer types. Because this analysis shows association rather than direction, both RAB27B-to-partner and partner-to-RAB27B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAB27B versus TCN1 in BRCA, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB27B→partner) and Y-score (partner→RAB27B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TCN1 →	+2.461	+0.659	.001	.006	3	7
COAD	CCDC68 →	+1.070	+0.846	<.001	<.001	3	7
BRCA	GTF2IP7 →	+1.085	+0.791	<.001	<.001	3	6
BRCA	BCAS1 →	+2.091	+0.862	<.001	<.001	3	6
LSCC	YEATS2 →	-0.678	-0.551	.001	.002	3	6
BRCA	SDR16C5 →	+1.773	+0.865	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,453 associations by consensus.

RAB27B vs TCN1 — BRCA

Explore this scatter interactively →