RAB27B

Across TCGA cell cohorts, RAB27B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,230 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RAB27B-associated GO terms across cancer lineages are Regulation of muscle system process, Regulation of protein localization to cell periphery, and Maintenance of protein location in cell. Each is linked with RAB27B in more than 12 cancer types. Because this analysis shows association rather than direction, both RAB27B-to-partner and partner-to-RAB27B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of muscle system process grouped by RAB27B-low versus RAB27B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB27B→partner) and Y-score (partner→RAB27B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of muscle system process →	+0.084	+1.325	<.001	.006	2	13
BONE	Regulation of protein localization to cell periphery →	+0.063	+1.161	.001	<.001	3	10
SOFT_TISSUE	Maintenance of protein location in cell →	+0.113	+1.194	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Macrophage colony-stimulating factor signaling pathway →	+1.469	+2.003	<.001	.001	3	10
SOFT_TISSUE	Maintenance of protein location →	+0.114	+1.190	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Cellular response to 2,3,7,8-tetrachlorodibenzodioxine →	+0.802	+1.709	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,230 associations by consensus.

Regulation of muscle system process by RAB27B expression — BONE

Explore this box plot interactively →