RAB14

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB14 mutation is significantly associated with the RNA expression of many other genes, with 1,901 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB14-associated genes across cancer lineages are RNA5SP413, RNA5SP411, and KRT18P45. Each is linked with RAB14 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB14-to-partner and partner-to-RAB14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by RAB14-low versus RAB14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB14→partner) and Y-score (partner→RAB14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP413 →+1.011+1.862<.001.00433
UCECRNA5SP411 →+0.970+2.256<.001<.00132
CESCKRT18P45 →+0.057+3.944<.001.00732
CESCRNU6-1067P →+0.487+4.984<.001.00332
UCECRNA5SP418 →+0.709+1.863<.001.00732
UCECRNA5SP410 →+0.761+2.374<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,901 associations by consensus.

RNA5SP413 by RAB14 expression — UCEC

Box plot of RNA5SP413 in RAB14-low vs RAB14-high samples in UCEC.

Explore this box plot interactively →

Exploration