RAB14

Across TCGA pan-cancer cohorts, RAB14 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RAB14’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RAB14 RNA is repressed in tumor relative to normal tissue. In most cancer types RAB14 is over-expressed in tumor, although a few such as LUAD and KIRC show the opposite, repressed pattern.

LUAD, KIRC, and HNSC are the cancer types where RAB14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	−0.761	<.001	8	view →
KIRC	Male	III,IV	−0.588	<.001	8	view →
HNSC	All	All	+0.331	.003	6	view →
KICH	Male	All	−0.860	<.001	5	view →
STAD	All	II,III,IV	+0.490	.006	5	view →
BRCA	All	II,III,IV	+0.142	.033	4	view →
LUSC	All	All	−0.268	.002	3	view →
UCEC	All	All	−0.650	.003	2	view →
READ	All	All	−0.368	.019	2	view →
COAD	All	All	−0.278	.007	2	view →
CHOL	All	All	+0.774	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RAB14–LUAD

Open the LUAD breakdown →