RAB11FIP4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB11FIP4 mutation is significantly associated with the RNA expression of many other genes, with 1,507 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB11FIP4-associated genes across cancer lineages are RNU6-1, NDUFA6, and SEC22B2P. Each is linked with RAB11FIP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB11FIP4-to-partner and partner-to-RAB11FIP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1 grouped by RAB11FIP4-low versus RAB11FIP4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP4→partner) and Y-score (partner→RAB11FIP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-1 →+0.402+1.819<.001<.00133
COADNDUFA6 →+0.608+3.348<.001.00533
CESCSEC22B2P →+0.065+3.890<.001.00132
UCECBUB3 →+0.334+2.882.004.00132
UCECMRPL39 →+0.367+1.959.001.00832
UCECSYNJ1 →+0.276+1.942.008.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,507 associations by consensus.

RNU6-1 by RAB11FIP4 expression — UCEC

Box plot of RNU6-1 in RAB11FIP4-low vs RAB11FIP4-high samples in UCEC.

Explore this box plot interactively →

Exploration