RAB11FIP4

Across TCGA pan-cancer cohorts, RAB11FIP4 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated RAB11FIP4 data layer compared with 1 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RAB11FIP4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RAB11FIP4 expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

KIRC, READ, and STAD are the cancer types where RAB11FIP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.710	0.551	<.001	88	view →
READ	OS	Tertile	All	0.983	0.825	.001	87	view →
STAD	OS	Quartile	All	0.746	0.589	.006	37	view →
LIHC	DFS	Tertile	All	0.449	0.665	<.001	33	view →
LAML	DFS	Tertile	All	0.244	0.541	.005	32	view →
COAD	OS	Tertile	All	0.894	0.762	.004	31	view →
HNSC	OS	Tertile	All	0.748	0.624	.013	31	view →
ESCA	OS	Median	All	0.440	1.000	.008	27	view →
UCEC	DFS	Quartile	II,III,IV	0.755	0.903	.013	22	view →
CHOL	DFS	Median	All	0.661	0.212	.004	19	view →
BRCA	DFS	Median	III,IV	0.861	0.727	.005	18	view →
LGG	DFS	Quartile	All	0.877	0.768	.004	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

RAB11FIP4–KIRC (OS)

Open the KIRC breakdown →