RAB11A

Across TCGA cell cohorts, RAB11A mutation is significantly associated with the mutation status of many other genes, with 1,575 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB11A-associated genes across cancer lineages are FAM172A, KIAA0319L, and GMPS. Each is linked with RAB11A in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB11A-to-partner and partner-to-RAB11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM172A grouped by RAB11A-low versus RAB11A-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11A→partner) and Y-score (partner→RAB11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FAM172A →	+6.044	+6.044	.001	.001	1	3
CNS	KIAA0319L →	+5.044	+5.614	.003	.003	1	3
CNS	GMPS →	+6.044	+6.044	.001	.001	1	3
CNS	PCCA →	+4.044	+5.000	.008	.008	1	3
LARGE_INTESTINE	RMND5A →	+4.087	+5.044	.001	.001	1	3
LARGE_INTESTINE	GABRA1 →	+4.087	+5.044	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,575 associations by consensus.

FAM172A by RAB11A expression — CNS

Explore this box plot interactively →