RAB11A

Across TCGA pan-cancer cohorts, RAB11A RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RAB11A’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RAB11A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAB11A is over-expressed in tumor, although a few such as LUAD and HNSC show the opposite, repressed pattern.

LIHC, BRCA, and CHOL are the cancer types where RAB11A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB11A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+0.907	<.001	9	view →
BRCA	All	All	+0.370	<.001	6	view →
CHOL	Female	All	+2.136	<.001	5	view →
BLCA	All	IV	+0.811	.004	5	view →
LUAD	Female	III,IV	−0.686	<.001	4	view →
HNSC	All	II,III,IV	−0.324	.015	3	view →
PRAD	All	All	+0.382	<.001	2	view →
READ	All	All	−0.378	.006	2	view →
KICH	All	All	−0.359	.016	2	view →
KIRP	Male	All	−0.291	.015	2	view →
KIRC	All	II,III,IV	−0.205	.030	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RAB11A–LIHC

Open the LIHC breakdown →