R3HDML

Across TCGA patient cohorts, R3HDML RNA expression is significantly associated with the go_rna of many other GO terms, with 7,094 significant associations in total. STAD shows the largest number of these associations.

The most reproducible R3HDML-associated GO terms across cancer lineages are Negative regulation of growth, Protein polymerization, and Positive regulation of organelle assembly. Each is linked with R3HDML in more than 18 cancer types. Because this analysis shows association rather than direction, both R3HDML-to-partner and partner-to-R3HDML results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of growth grouped by R3HDML-low versus R3HDML-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (R3HDML→partner) and Y-score (partner→R3HDML) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of growth →	+0.047	+0.398	<.001	<.001	3	19
STAD	Protein polymerization →	+0.041	+0.383	<.001	<.001	3	17
ESCA	Positive regulation of organelle assembly →	+0.065	+0.508	<.001	<.001	3	17
STAD	Glycerolipid biosynthetic process →	+0.049	+0.448	<.001	<.001	3	17
STAD	Protein polyubiquitination →	+0.052	+0.438	<.001	<.001	3	17
STAD	Negative regulation of Wnt signaling pathway →	+0.047	+0.506	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,094 associations by consensus.

Negative regulation of growth by R3HDML expression — STAD

Explore this box plot interactively →