R3HDML

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, R3HDML protein abundance is significantly associated with the go_rna of many other GO terms, with 1 significant associations in total. GBM shows the largest number of these associations.

The most reproducible R3HDML-associated GO terms across cancer lineages are Benzene-containing compound metabolic process. Each is linked with R3HDML in more than 1 cancer types. Because this analysis shows association rather than direction, both R3HDML-to-partner and partner-to-R3HDML results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Benzene-containing compound metabolic process grouped by R3HDML-low versus R3HDML-high in GBM.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (R3HDML→partner) and Y-score (partner→R3HDML) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMBenzene-containing compound metabolic process →+0.099+0.253.004.00221
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Benzene-containing compound metabolic process by R3HDML expression — GBM

Box plot of Benzene-containing compound metabolic process in R3HDML-low vs R3HDML-high samples in GBM.

Explore this box plot interactively →

Exploration